Hemophagocytic lymphohistiocytosis with hepatitis A

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hemophagocytic lymphohistiocytosis-a rare complication of hepatitis a virus infection

introduction hemophagocytic lymphohistiocytosis (hlh) is a heterogeneous group of clinical syndromes characterized by activation and subsequent uncontrolled non-malignant proliferation of t-lymphocytes, histiocytes and macrophages leading to a cytokine storm and manifesting as prolonged fever, organomegaly, cytopenia, hyperferritinemia and demonstrable hemophagocytosis in the bone marrow. concl...

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Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of excessive immune activation causing widespread inflammation and tissue destruction leading to multi-organ dysfunction and failure. Making the diagnosis of HLH could be quite challenging due to the broad range of presenting symptoms and their lack of specificity. After ruling out considerations for differential diagnoses, recognizing the ...

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ژورنال

عنوان ژورنال: Journal of Applied Hematology

سال: 2013

ISSN: 1658-5127

DOI: 10.4103/1658-5127.127903